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GEMZAR
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 GEMZAR
 
Package(a):
VIAL (powder for solution for infusion): 1 x 200 mg.

Dosage(a):
Should only be prescribed by a physician qualified in the use of anti-cancer chemotherapy.
Non-Small Cell Lung Cancer: Combination use: Adults: Gemcitabine in combination with cisplatin has been investigated using two dosing regimens. One regimen used a three week schedule and the other used a four week schedule. The three week schedule used gemcitabine 1,250 mg/m2, given by 30 minute IV infusion, on days 1 and 8 of each 21 day cycle. The four week schedule used gemcitabine 1000 mg/m2, given by 30 minute IV infusion, on days 1, 8, 15 of each 28 day cycle. Cisplatin has been used at doses between 75-100 mg/m2 once every 3 or 4 weeks. Single-agent use: Adults: The recommended dose of gemcitabine is 1,000 mg/m2, given by 30 minute IV infusion. This should be repeated 1x weekly for three weeks, followed by a one week rest period. This four week cycle is then repeated. See prescribing information for full details.
Breast cancer: Combination use: Adults: Gemcitabine in combination with paclitaxel is recommended using paclitaxel (175 mg/m2) administered on Day 1 over approximately 3 hours as an IV infusion, followed by gemcitabine (1,250 mg/m2) as a 30-minute intravenous infusion on Days 1 and 8 of each 21-day cycle. See prescribing information for full details.
Pancreatic Cancer: Adults: The recommended dose of gemcitabine is 1,000 mg/m2 given by 30¬minute IV infusion. This should be repeated 1 x weekly for up to 7 weeks, followed by a week of rest. Subsequent cycles should consist of injections 1 x weekly for 3 consecutive weeks out of every 4 weeks. See prescribing information for full details.
Bladder Cancer: Combination use: Adults: The recommended dose for gemcitabine is 1,000 mg/m2, given by 30 minute infusion. The dose should be given on days 1, 8, and 15 of each 28 day cycle in combination with cisplatin. Cisplatin is given at a recommended dose of 70 mg/m2 on day 1 following gemcitabine or day 2 of each 28 day cycle. This four week cycle is then repeated. See prescribing information for full details.
Ovarian cancer: Combination use: Adults: Gemcitabine in combination with carboplatin is recommended using gemcitabine 1,000 mg/m2 administered on Days 1 and 8 of each 21-day cycle as a 30-minute IV infusion. After gemcitabine, carboplatin will be given on Day 1 consistent with a target AUC of 4.0 mg/ml*min. See prescribing information for full details.

Prescribing Restrictions:  None

Package(b):
VIAL (powder for solution for infusion): 1 x 1,000 mg